Consecuencia de todas las explicaciones que he mencionado hasta ahora, la teoría de la infraconectividad postula que las conexiones entre distintas áreas cerebrales estaría disminuida o tendría menor eficacia en el autismo.
Efectivamente, tanto las interferencias por posiciones neuronales anómalas –defectos de la migración–, como el defecto de coordinación cerebelosa –déficit de células de Purkinje–, el enlentecimiento en la transmisión de la información –exceso de ramificaciones dendríticas–, y la alteración de la estructura de las unidades de información –alteración de las microcolumnas corticales– tienen como consecuencia una disminución de la conexión entre neuronas.
Además la alteración en el sistema de neuronas espejo empeoraría las posibilidades de compensar esta infraconectividad.
Esta teoría está basada en los resultados de estudios con resonancia magnética funcional que miden la activación de áreas cerebrales durante el desempeño de diferentes tareas.
Comparando los resultados entre niños sin y con autismo, pero con el mismo cociente intelectual, se encuentran claras diferencias. Los niños con autismo muestran una activación diferente y una disminución en la conectividad entre distintas áreas.
Fuente: Neuronas en Crecimiento de María José Mas
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