la neuro-anatomía en el autismo
Intentar explicar las alteraciones cerebrales en el autismo es muy complejo. El autismo es un trastorno que afecta al desarrollo cerebral –neurodesarrollo– y que produce dificultades en la comunicación y la interacción social.
En neuropediatría, tras recoger los síntomas y signos que presenta el paciente, se busca su correlato anatómico. Cuando se nos presenta un niño con autismo, esto ni es fácil ni disponemos de herramientas diagnósticas para hacerlo en la clínica diaria.
Entre los síntomas nucleares del autismo –trastorno de la comunicación, de la sociabilidad e intereses poco variados–, es difícil encontrar un nexo común que nos permita situar estas alteraciones en una zona restringida del cerebro.
El autismo se resiste a ser explicado por el método neurológico clásico. Las explicaciones neuroanatómicas no consiguen dar una respuesta definitiva a la “coincidencia” de los síntomas del autismo.
Continuamente aparecen noticias que hablan de alteraciones anatómicas halladas en el cerebro de las personas que padecen autismo, pero son alteraciones inconexas que se quedan pobres para explicar la complicada y variada sintomatología del autismo.
Hablé anteriormente sobre los procesos mentales que subyacen a la sintomatología del autismo. En esta entrada intentaré resumir las alteraciones neuronales, tisulares y anatómicas más conocidas del cerebro autista.
En la siguiente dedicada a los “mecanismos” cerebrales del autismo hablaré de la genética.
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