LA GENETICA EN TEA

Se han realizado estudios de gemelos y de familias que sugieren fuertemente que algunas personas tienen una predisposición genética a los trastornos del espectro autista.

Los estudios de gemelos idénticos demuestran que, si un gemelo está afectado, entonces el otro estará afectado entre el 35 y 95 por ciento de las veces.

Se están llevando a cabo diversos estudios para determinar los factores genéticos específicos asociados con la presencia de trastornos del espectro autista.

Dentro de las familias con un niño con un trastorno del espectro autista, el riesgo de tener otro niño con el trastorno también aumenta.

Muchos de los genes que se encontraron asociados con los trastornos del espectro autista están involucrados en la función de las conexiones químicas entre las neuronas cerebrales (sinapsis).

Los investigadores están buscando pistas sobre cuáles genes contribuyen al aumento en la susceptibilidad.

En algunos casos, los padres y otros parientes de un niño con un trastorno del espectro autista muestran problemas leves de comunicación social o se involucran en comportamientos repetitivos.

La evidencia también sugiere que los trastornos emocionales como el trastorno bipolar y la esquizofrenia se presentan con más frecuencia de la normal en las familias de personas con trastornos del espectro autista.

Además de las variaciones genéticas que se heredan y están presentes en casi todas las células de una persona, las investigaciones recientes también han demostrado que las mutaciones de novo o espontáneas de los genes pueden influenciar el riesgo de desarrollar trastornos del espectro autista.

Las mutaciones de novo son cambios en las secuencias del ácido desoxirribonucleico o ADN, es decir, en el material hereditario en los seres humanos, que pueden ocurrir espontáneamente en los espermatozoides, en el óvulo o durante la fecundación.

Esta mutación continúa repitiéndose en cada célula a medida que el óvulo fecundado se divide. Estas mutaciones pueden afectar un solo gen o puede haber cambios conocidos como “variaciones en el número de copias”, en las cuales se suprimen o se duplican fragmentos de ADN que contienen varios genes.

Algunos estudios recientes han demostrado que las personas con trastornos del espectro autista tienden a tener más mutaciones genéticas de novo del tipo “variaciones en el número de copias” que las personas que no tienen estos trastornos.

Esto sugiere que, en algunos casos, el riesgo de desarrollar trastornos del espectro autista no es el resultado de mutaciones en genes individuales, sino más bien de mutaciones de codificación espontáneas en muchos genes.

Las mutaciones de novo pueden explicar los trastornos genéticos en los cuales el niño afectado tiene la mutación en cada célula, pero sus padres no la tienen y tampoco hay ningún patrón familiar del trastorno.

El riesgo de los trastornos del espectro autista también aumenta en los niños nacidos de padres de mayor edad.

Todavía se requiere mucha investigación para determinar el papel potencial de los factores ambientales en las mutaciones espontáneas y cómo influyen en el riesgo de desarrollar los trastornos del espectro autista.

FUENTE: NIH, El NINDS tiene la misión de adquirir un conocimiento fundamental sobre el cerebro y el sistema nervioso y utilizar este conocimiento para reducir la carga de las enfermedades neurológicas.

Esta entrada fue publicada en AUTISMO, DIVULGACIÓN. Guarda el enlace permanente.

55 respuestas a LA GENETICA EN TEA

  1. It’s the best time to make some plans for the
    future and it’s time to be happy. I’ve read this post and if I could I desire to suggest you some interesting things or suggestions.

    Perhaps you could write next articles referring to this article.
    I wish to read more things about it! asmr 0mniartist

  2. Write more, thats all I have to say. Literally, it seems as though you relied on the video
    to make your point. You clearly know what youre talking about, why waste your intelligence on just posting videos to your blog when you could be
    giving us something enlightening to read? asmr 0mniartist

  3. 0mniartist dijo:

    Hey there just wanted to give you a quick heads up.

    The words in your content seem to be running off the screen in Opera.
    I’m not sure if this is a formatting issue or something to do with web browser compatibility but I figured I’d post to let
    you know. The design and style look great though!

    Hope you get the problem resolved soon. Thanks 0mniartist asmr

  4. Does your site have a contact page? I’m having trouble locating it but, I’d like to send you an e-mail.
    I’ve got some suggestions for your blog you might be interested in hearing.
    Either way, great site and I look forward to seeing it grow over time.
    0mniartist asmr

  5. bit.ly dijo:

    I do consider all the ideas you have introduced for
    your post. They’re really convincing and can certainly work.

    Nonetheless, the posts are very brief for starters.
    May just you please lengthen them a bit from subsequent time?
    Thank you for the post. 0mniartist asmr

  6. with asmr dijo:

    Hi it’s me, I am also visiting this web page daily, this site is in fact pleasant
    and the visitors are genuinely sharing pleasant
    thoughts.

  7. asmr off dijo:

    You need to take part in a contest for one of the best
    sites on the net. I most certainly will recommend this web site!

  8. a gamefly dijo:

    Hi, i think that i saw you visited my site thus i came to “return the favor”.I am trying to find things to improve
    my site!I suppose its ok to use a few of your ideas!!

  9. of asmr dijo:

    It’s actually a nice and helpful piece of information. I’m glad that you simply shared this helpful
    info with us. Please keep us up to date like this. Thank you
    for sharing.

  10. bit.ly dijo:

    We’re a gaggle of volunteers and starting a brand new scheme in our community.
    Your web site offered us with useful info to work on. You have performed a formidable task and our entire community can be thankful to you.

  11. scoliosis
    I am actually pleased to read this web site posts which includes lots of helpful data, thanks for providing such information. scoliosis

  12. free dating sites
    Hey! Do you use Twitter? I’d like to follow you if that would be ok.
    I’m undoubtedly enjoying your blog and look forward to new updates.
    https://785days.tumblr.com/ dating sites

  13. asmr a dijo:

    This excellent website truly has all of the info I wanted about this subject
    and didn’t know who to ask.

  14. Every weekend i used to visit this site, because i wish for enjoyment, for the reason that
    this this site conations in fact good funny information too.

  15. my scoliosis dijo:

    Greate pieces. Keep writing such kind of info on your site.
    Im really impressed by it.
    Hey there, You’ve performed an incredible job. I will certainly
    digg it and in my view suggest to my friends.

    I am confident they will be benefited from this website.

  16. Dominick dijo:

    Pretty part of content. I simply stumbled upon your website and in accession capital to assert that
    I get in fact loved account your weblog posts. Anyway I’ll
    be subscribing for your feeds or even I success you get admission to consistently quickly.

  17. Kenny dijo:

    Hi there, I discovered your blog by the use of
    Google even as searching for a comparable subject, your
    website came up, it seems to be great. I have bookmarked it in my google
    bookmarks.
    Hello there, simply changed into aware of your blog thru Google, and found that it’s
    truly informative. I am gonna be careful for brussels.
    I’ll appreciate should you proceed this in future.
    Numerous other folks might be benefited from your writing.

    Cheers!

  18. Nice post. I learn something new and challenging on blogs I stumbleupon every
    day. It’s always helpful to read articles from other authors and practice something from their websites.

  19. tinyurl.com dijo:

    My spouse and I stumbled over here different page and thought I might as
    well check things out. I like what I see so now i am following you.
    Look forward to exploring your web page repeatedly.

  20. zortilo nrel dijo:

    Greetings from Los angeles! I’m bored to death at work so I decided to browse your website on my iphone during lunch break. I love the info you present here and can’t wait to take a look when I get home. I’m shocked at how quick your blog loaded on my mobile .. I’m not even using WIFI, just 3G .. Anyways, great blog!

  21. I know this if off topic but I’m looking into starting my own blog and was
    curious what all is required to get setup? I’m assuming having a blog like yours
    would cost a pretty penny? I’m not very internet savvy so I’m not 100% certain. Any suggestions
    or advice would be greatly appreciated. Cheers

  22. Right away I am going to do my breakfast, when having my breakfast coming yet again to read other news.

  23. Very nice post. I just stumbled upon your weblog and wished to say
    that I’ve truly enjoyed browsing your blog posts.

    In any case I’ll be subscribing to your rss feed and I hope you
    write again soon!

  24. I love what you guys are usually up too. This sort of clever work and reporting!

    Keep up the fantastic works guys I’ve incorporated you guys to my own blogroll.

  25. What’s up, the whole thing is going nicely here and ofcourse
    every one is sharing information, that’s in fact
    excellent, keep up writing.

  26. With havin so much content do you ever run into any problems
    of plagorism or copyright violation? My blog has a
    lot of unique content I’ve either written myself
    or outsourced but it appears a lot of it is popping it up all over the web without my agreement.
    Do you know any methods to help protect against content from being stolen? I’d really appreciate it.

  27. Everything is very open with a precise clarification of the issues.
    It was truly informative. Your site is very useful.
    Thank you for sharing!

  28. I think the admin of this site is in fact working hard for his site, for the reason that here every
    stuff is quality based information.

  29. gamefly dijo:

    I’m amazed, I must say. Seldom do I come across a blog that’s both educative and entertaining, and without a doubt, you’ve hit the nail
    on the head. The problem is an issue that not
    enough folks are speaking intelligently about. I’m very happy that I came across this in my search for something concerning this.

  30. Gaston Merli dijo:

    Where can I find blogging websites that deal with legal issues?

  31. gamefly dijo:

    Asking questions are truly pleasant thing if you are
    not understanding anything entirely, but this piece
    of writing provides nice understanding yet.

  32. I am sure this piece of writing has touched all the internet viewers, its really really good article on building up
    new web site.

  33. Assume that you are working as a computer technician for a company with a large network. You are assigned to determine what is wrong with an employee?s computer and repair it. You suspect that the computer is not properly connected to the network. Describe the troubleshooting steps you would take to test your theory that the computer is not physically or logically connected to the network, and describe how you would resolve the resolve the various reasons for the computer not connecting to the network..

  34. bit.ly dijo:

    Heya i’m for the first time here. I came across this board
    and I in finding It truly helpful & it helped me out a lot.

    I’m hoping to provide something again and help others like you aided
    me.

  35. http://t.co/ dijo:

    I just like the valuable info you provide to
    your articles. I’ll bookmark your weblog and take a look at once more
    here frequently. I’m slightly certain I will be told lots of new stuff proper right here!
    Good luck for the following!

  36. Hi there, yes this paragraph is actually good and I have learned lot of things
    from it on the topic of blogging. thanks.

  37. Excellent site. Plenty of useful information here.
    I’m sending it to some friends ans additionally sharing in delicious.
    And certainly, thank you in your effort!

  38. tinyurl.com dijo:

    Hi there, You have done an excellent job. I will definitely digg it and personally recommend to my friends.

    I’m confident they will be benefited from this website.

  39. tinyurl.com dijo:

    magnificent issues altogether, you just received a emblem new reader.
    What would you recommend about your submit that you
    just made some days ago? Any certain?

  40. tinyurl.com dijo:

    With havin so much content and articles do you ever run into
    any problems of plagorism or copyright infringement? My
    site has a lot of exclusive content I’ve either created
    myself or outsourced but it appears a lot of it is popping it up all over the internet without my authorization. Do you know any methods to help reduce content from being
    stolen? I’d definitely appreciate it.

  41. tinyurl.com dijo:

    Unquestionably believe that which you said.
    Your favourite justification seemed to be at the internet the easiest thing to consider of.
    I say to you, I definitely get irked even as folks consider concerns that they just don’t understand about.
    You managed to hit the nail upon the top as well as outlined out the entire
    thing with no need side-effects , people could take a signal.
    Will likely be back to get more. Thanks

  42. I was very happy to find this great site. I wanted to thank you for your time just for this fantastic read!!
    I definitely savored every part of it and i also have you book marked to check out new things in your website.

  43. tinyurl.com dijo:

    My spouse and I stumbled over here by a different web page and
    thought I should check things out. I like what
    I see so i am just following you. Look forward
    to going over your web page again.

  44. WOW just what I was searching for. Came here by
    searching for what

  45. tinyurl.com dijo:

    What’s up, yes this post is in fact nice and I have learned lot of things from it on the topic of blogging.

    thanks.

  46. tinyurl.com dijo:

    After I originally left a comment I appear to have clicked the
    -Notify me when new comments are added- checkbox and now every time a comment is added I get four emails with the exact same comment.
    Is there a means you can remove me from that service? Thank you!

  47. Hello, i read your blog from time to time and i own a
    similar one and i was just wondering if you get a lot
    of spam comments? If so how do you protect against it,
    any plugin or anything you can suggest? I get so much lately
    it’s driving me insane so any assistance is very much appreciated.

  48. tinyurl.com dijo:

    I have been exploring for a little for any high quality articles or weblog posts on this kind
    of area . Exploring in Yahoo I ultimately stumbled upon this site.
    Reading this information So i am satisfied to exhibit
    that I have a very excellent uncanny feeling I came upon exactly what I needed.
    I most indisputably will make sure to don?t put out of your mind this site and give
    it a look regularly.

  49. tinyurl.com dijo:

    I am really delighted to read this website posts which consists of
    tons of valuable data, thanks for providing these data.

  50. Excellent goods from you, man. I’ve understand your stuff previous to and you’re just
    too great. I really like what you have acquired here, really
    like what you’re stating and the way in which you say it.
    You make it entertaining and you still take care of to keep it sensible.
    I can’t wait to read far more from you. This is really a great website.

  51. Thanks for sharing excellent informations. Your web-site is so cool. I am impressed by the details that you have on this site. It reveals how nicely you understand this subject. Bookmarked this website page, will come back for more articles. You, my pal, ROCK! I found just the info I already searched all over the place and simply could not come across. What a great website.

  52. special dijo:

    Hi everybody, here every one is sharing such knowledge,
    therefore it’s fastidious to read this web site, and I used to pay a visit this blog everyday.

    Also visit my homepage: special

  53. There is perceptibly a bundle to realize about this. I suppose you made various good points in features also.

  54. It is actually a nice and useful piece of information. I¦m satisfied that you just shared this helpful info with us. Please keep us up to date like this. Thank you for sharing.

  55. gate io dijo:

    I may need your help. I tried many ways but couldn’t solve it, but after reading your article, I think you have a way to help me. I’m looking forward for your reply. Thanks.

Deja una respuesta

Tu dirección de correo electrónico no será publicada. Los campos obligatorios están marcados con *